LAQV REQUIMTE

(Chemical) Bonding is what makes life possible

Marta S. P. Carepo

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Research group
Omics and Analytical Development

Position
Academic Staff

My main research areas are Biochemistry, Molecular Biology, Biophysics, Biomolecular Spectroscopy of Metalloproteins, Heterologous Expression of Metalloproteins, Protein-Protein Interactions, Stress response to metals and oxygen and studies of interaction between metallodrugs and biomolecules. I am particularly involved in the study of oxygen heme sensors from Mycobacterium tuberculosis and heavy metal and thermal bacterial response systems. I have published 41 peer-reviewed papers, 1 Book Chapters, and I have an h-factor of 11. I supervised 1 Pos-doc, 3 PhD students (2 on-going), 3 Master students, 7 BSc. students, 4 IAESTE and 5 BII scholarships.

Representative Publications

ArsC3 from Desulfovibrio alaskensis G20, a cation and sulfate-independent highly efficient arsenate reductase
10.1007/s00775-014-1184-8
Mo-Cu metal cluster formation and binding in an orange protein isolated from Desulfovibrio gigas
10.1007/s00775-014-1107-8
Orange protein from Desulfovibrio alaskensis G20: insights into the Mo-Cu cluster protein-assisted synthesis
10.1007/s00775-015-1323-x
Molybdenum Induces the Expression of a Protein Containing a New Heterometallic Mo-Fe Cluster in Desulfovibrio alaskensis
10.1021/65801773t
Insights into signal transduction by a hybrid FixL: Denaturation study of on and off states of a multi-domain oxygen sensor
10.1016/j.jinorgbio.2017.04.013
Hydroxyl Radical Generation and DNA Nuclease Activity: A Mechanistic Study Based on a Surface-Immobilized Copper Thioether Clip-Phen Derivative
10.1002/chem.201601719
The Heme-Based Oxygen Sensor Rhizobium etli FixL: Influence of Auxiliary Ligands on Heme Redox Potential and Implications on the Enzyme Activity
10.1016/j.jinorgbio.2016.08.009