LAQV REQUIMTE

(Chemical) Bonding is what makes life possible

Joana Cristina Barbosa Loureiro

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I obtained my degree in Biochemistry at Universidade de Aveiro. My MSc studies in Biochemistry were obtained at Faculty of Science, University of Porto, under the supervision of Prof. L. Saraiva, involved the molecular and pharmacological studies of the most prevalent mutant p53 forms. Currently, I'm attending the Pharmaceutical Sciences PhD in Faculty of Pharmacy, University of Porto.

Representative Publications

DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties
10.1002/1878-0261.12051
Improving anticancer activity towards colon cancer cells with a new p53-activating agent
10.1111/bph.14468
BRCA1/P53: Two strengths in cancer chemoprevention
10.1016/j.bbcan.2020.188339
Targeting the MDM2-p53 protein-protein interaction with prenylchalcones: Synthesis of a small library and evaluation of potential antitumor activity
10.1016/j.ejmech.2018.07.037
SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma
10.3390/cancers11081151