LAQV REQUIMTE

(Chemical) Bonding is what makes life possible

João Paulo Grosso Pacheco

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Research group
Environmental Chemistry

Position
Researcher

Researcher IDD-8599-2013
Ciência ID8D13-F178-F44D
I was awarded a predoctoral grant from FCT in 2006 and I obtained my PhD in Analytical Chemistry from Faculty of Sciences - University of Porto (FCUP) in 2010, where I developed strong skills in analytical chemistry, particularly sample preparation tools, electrochemical detection, and chromatographic methods. My work resulted in a Portuguese patent.
Then I was awarded postdoc grant from FCT and move to GRAQ/ISEP/REQUIMTE to work in the environmental area in the development of methods for pharmaceutical pollution. I was also able to learn new skills such as remediation procedures, synthesis of nanomaterials and help in the development of green remediation procedures with papers with high citation score. In 2013 I proposed to start a MIP sensors research line at GRAQ/ISEP/REQUIMTE that could answer to several analytical challenges in the group. I was awarded with another FCT postdoc grant exclusively focused MIP sensors. I am the scientific leader of this research line. I contributed to improve the state-of-the-art of the field with several publications in reference journals, and applied the sensors in different areas, mainly in the environmental area but also in health (cancer biomarkers) and food (safety and quality control). I developed skills on different polymerization procedures and several possibilities for sensors construction. I acquired experience using different types of conductive nanomaterials and methods of preparation. From conventional electrodes I moved to disposable commercially available electrodes to try to achieve low cost and portability.
I am author of more than 40 research papers in peer-reviewed journals and 2 book chapters. Their relevance for peers is reflected by my h-index of 24 and total citation score of 2268 (Scopus). He is currently PI of a competitive national project founded be FCT.


Representative Publications

Green zero-valent iron nanoparticles for the degradation of amoxicillin
10.1007/s13762-016-1197-7
Molecularly imprinted electrochemical sensor prepared on a screen printed carbon electrode for naloxone detection
10.1016/j.snb.2016.12.031
Cometabolic Degradation of Anti-Inflammatory and Analgesic Pharmaceuticals by a Pentane Enrichment Culture
10.1007/s11270-016-2933-9
Characterization of green zero-valent iron nanoparticles produced with tree leaf extracts
10.1016/j.scitotenv.2015.06.091
Molecularly imprinted sensor for voltammetric detection of norfloxacin
10.1016/j.snb.2015.04.125
Molecularly imprinted electrochemical sensor for ochratoxin A detection in food samples
10.1016/j.snb.2015.03.046
Utilization of food industry wastes for the production of zero-valent iron nanoparticles
10.1016/j.scitotenv.2014.07.058
MIP-graphene-modified glassy carbon electrode for the determination of trimethoprim
10.1016/j.bios.2013.08.035
Application of green zero-valent iron nanoparticles to the remediation of soils contaminated with ibuprofen
10.1016/j.scitotenv.2013.05.016
Voltammetric analysis of metallothioneins and copper (II) in fish for water biomonitoring studies
10.1007/s10311-010-0293-z
Determination of free and total sulfites in wine using an automatic flow injection analysis system with voltammetric detection
10.1080/19440040903261547
Breast cancer biomarker (HER2-ECD) detection using a molecularly imprinted electrochemical sensor
10.1016/j.snb.2018.06.113
21 - Biosensors A2 - Larroche, Christian
10.1016/B978-0-444-63663-8.00021-5
Green production of zero-valent iron nanoparticles using tree leaf extracts
10.1016/j.scitotenv.2012.12.033
Determination of free and total diacetyl in wine by HPLC-UV using gas-diffusion microextraction and pre-column derivatization
10.1016/j.foodcont.2011.07.017
Gas-diffusion microextraction
10.1002/jssc.201000351
Analysis of aldehydes in beer by gas-diffusion microextraction: Characterization by high-performance liquid chromatography-diode-array detection-atmospheric pressure chemical ionization-mass spectrometry
10.1016/j.chroma.2010.04.002
Polarographic determination of vitamin C after derivatization with o-phenylenediamine
10.1135/cccc2010026
Use of a membraneless extraction module for the voltammetric determination of total sulfites in wine
10.1135/cccc2009558
Development of a membraneless extraction module for the extraction of volatile compounds: Application in the chromatographic analysis of vicinal diketones in beer
10.1016/j.talanta.2009.12.011
Molecularly imprinted electrochemical sensor for the point-of-care detection of a breast cancer biomarker (CA 15-3)
10.1016/j.snb.2017.10.027
Influence of malt on the xanthohumol and isoxanthohumol behavior in pale and dark beers: A micro-scale approach
10.1016/j.foodres.2010.10.008
The Impact of Xanthohumol on a Brewing Yeast's Viability, Vitality and Metabolite Formation
10.1002/j.2050-0416.2011.tb00481.x
Isolation of phenolic compounds from hop extracts using polyvinylpolypyrrolidone: Characterization by high-performance liquid chromatography-diode array detection-electrospray tandem mass spectrometry
10.1016/j.chroma.2009.10.068
Magnetic dispersive micro solid-phase extraction and gas chromatography determination of organophosphorus pesticides in strawberries
10.1016/j.chroma.2018.06.045
New designs for inhibitors of the NF-kappa B: DNA binding
10.1007/s00214-005-0628-1
Electrochemical sensing of the thyroid hormone thyronamine (T(0)AM) via molecular imprinted polymers (MIPs)
10.1016/j.talanta.2018.10.090
Electrochemical sensing of ecstasy with electropolymerized molecularly imprinted poly(o-phenylenediamine) polymer on the surface of disposable screen-printed carbon electrodes
10.1016/j.snb.2019.03.138
Evaluation of the QuEChERS and magnetic micro dispersive solid-phase extraction of brominated flame retardants in red fruits with determination by GC/MS
10.1016/j.foodchem.2019.125572
Azithromycin electrochemical detection using a molecularly imprinted polymer prepared on a disposable screen-printed electrode
10.1039/c9ay02566a
Chemically modified and enzymatic electrochemical (bio)sensors for antidepressant drug detection: a review
Biosensors
Molecularly imprinted polymer-based electrochemical sensors for environmental analysis
10.1016/j.bios.2020.112719
Organochlorine pesticide analysis in milk by gas-diffusion microextraction with gas chromatography-electron capture detection and confirmation by mass spectrometry
10.1016/j.chroma.2020.461797
Low Cost, Easy to Prepare and Disposable Electrochemical Molecularly Imprinted Sensor for Diclofenac Detection
10.3390/s21061975
Development of a molecular imprinted electrochemiluminescence sensor for amitriptyline detection: From MD simulations to experimental implementation
10.1016/j.electacta.2021.139273
p A simple electrochemical detection of atorvastatin based on disposable screen-printed carbon electrodes modified by molecularly imprinted polymer: Experiment and simulation
10.1016/j.aca.2021.339410
Electropolymerized, Molecularly Imprinted Polymer on a Screen-Printed Electrode-A Simple, Fast, and Disposable Voltammetric Sensor for Trazodone
10.3390/s22072819
Computational Modelling and Sustainable Synthesis of a Highly Selective Electrochemical MIP-Based Sensor for Citalopram Detection
10.3390/molecules27103315
Electrochemical Chemically Based Sensors and Emerging Enzymatic Biosensors for Antidepressant Drug Detection: A Review
10.3390/ijms24108480
Molecularly Imprinted Plasmonic Sensors for the Determination of Environmental Water Contaminants: A Review
10.3390/chemosensors11060318
Analysis of atorvastatin in environmental waters: Validation of an electrochemical molecularly imprinted polymer sensor with application of life cycle assessment
10.1016/j.scitotenv.2024.171169
Electrochemical Sensors and (Bio)assays for Health Applications