Research group
Molecular Synthesis
Position
Academic Staff
BSc in Chemistry 1989; PhD in Chemistry 2000.
Professor at the Department of Chemistry and Biochemistry at the University of Porto.
Main interests: Assymetric synthesis of organic compounds; synthesis of amino acid-based surfactants for therapeutic applications (drug and gene delivery, antimicrobial activity).
Representative Publications
Enhancing glioblastoma cell sensitivity to chemotherapeutics: A strategy involving survivin gene silencing mediated by gemini surfactant-based complexes
10.1016/j.ejpb.2016.04.014
Novel serine-based gemini surfactants as chemical permeation enhancers of local anesthetics: A comprehensive study on structure-activity relationships, molecular dynamics and dermal delivery
10.1016/j.ejpb.2015.02.024
Gemini Surfactants Mediate Efficient Mitochondrial Gene Delivery and Expression
10.1021/mp5005349
Surface charge tunable catanionic vesicles based on serine-derived surfactants as efficient nanocarriers for the delivery of the anticancer drug doxorubicin
10.1039/c8nr06346j
