LAQV REQUIMTE

(Chemical) Bonding is what makes life possible

David Alexandre Micael Pereira

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Research group
Omics and Analytical Development

Position
Academic Staff

Researcher IDM-9286-2013
Ciência ID2918-F164-3036
David Pereira is Assistant Professor at the Faculty of Pharmacy, University of Porto, and senior researcher at LAQV@REQUIMTE.
He has an Integrated Master Degree and a PhD in Pharmaceutical Sciences from the Faculty of Pharmacy, University of Porto.

His research interests focus in natural products chemistry and bioactivity, with particular focus in cancer, inflammation and proteostasis.

He is also interested in health metrics and big data, with increasing interest in machine learning.

Representative Publications

Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016
Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the Global Burden of Disease Study 2015
10.1016/S0140-6736(17)30818-8
Neurotoxicity of the steroidal alkaloids tomatine and tomatidine is RIP1 kinase- and caspase-independent and involves the eIF2 alpha branch of the endoplasmic reticulum
10.1016/j.jsbmb.2017.03.009
Future and potential spending on health 2015-40: development assistance for health, and government, prepaid private, and out-of-pocket health spending in 184 countries
10.1016/S0140-6736(17)30873-5
Translating endoplasmic reticulum biology into the clinic: a role for ER-targeted natural products?
10.1039/c4np00102h
Anti-Inflammatory Effect of Unsaturated Fatty Acids and Ergosta-7,22-dien-3-ol from Marthasterias glacialis: Prevention of CHOP-Mediated ER-Stress and NF-kappa B Activation
10.1371/journal.pone.0088341
Natural Pigments of Anthocyanin and Betalain for Coloring Soy-Based Yogurt Alternative
10.3390/foods9060771
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
10.17863/cam.30678
Translating endoplasmic reticulum biology into clinic: a role for ER-targeted natural products?
Biological Evaluation of Naproxen–Dehydrodipeptide Conjugates with Self-Hydrogelation Capacity as Dual LOX/COX Inhibitors
10.3390/pharmaceutics12020122
Dehydropeptide-based plasmonic magnetogels: a supramolecular composite nanosystem for multimodal cancer therapy
10.1039/c9tb01900f
Anti-Inflammatory Effects of 5 alpha,8 alpha-Epidioxycholest-6-en-3 beta-ol, a Steroidal Endoperoxide Isolated from Aplysia depilans, Based on Bioguided Fractionation and NMR Analysis
10.3390/md17060330
Magnetic Dehydrodipeptide-Based Self-Assembled Hydrogels for Theragnostic Applications
10.3390/nano9040541
New chalcone-type compounds and 2-pyrazoline derivatives: synthesis and caspase-dependent anticancer activity
10.4155/fmc-2019-0342
Benzoquinones from Cyperus spp. trigger IRE1a-independent and PERK-dependent ER stress in human stomach cancer cells and are novel proteasome inhibitors
10.1016/j.phymed.2019.153017
Health effects of dietary risks in 195 countries, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017
10.1016/S0140-6736(19)30041-8
Past, present, and future of global health financing: a review of development assistance, government, out-of-pocket, and other private spending on health for 195 countries, 1995-2050
10.1016/S0140-6736(19)30841-4