Research group
Molecular Synthesis
Position
PhD student
My name is Daniela Malafaia, I am 27 years old and I am from Aveiro, Portugal. In 2018, I graduated in Biochemistry, at University of Aveiro (UA) and three years later, in 2021, I obtained my master's degree in Biochemistry (specialization in Clinical Biochemistry), at the same Institution. Later in the same year, I started my professional career, as a Quality Control Technician at Torrecid Portugal, a regional branch of the multinational company Torrecid S.A. Currently, I am a FCT-funded Ph.D. student (2021.05641.BD) at LAQV/REQUIMTE (UA), working on the development of a new strategy to adress the treatment of neurodegenerative disorders, through the synthesis and biological evaluation of a new class of chromenoxanthone-based molecules. I also published 5 articles in peer-review SCI international journals, 5 oral communications and 6 poster communications, in national and international scientific meetings. Throughout my academic journey, I was involved in multiple extracurricular projects, as a member and team leader of a junior company, students nuclei and voluntary associations. Currently, I am a board member at the Young Chemists Group (GQJ) of the Portuguese Society of Chemistry (SPQ), which aims to promote science outreach and public engagement activities related to the Chemistry field.
Representative Publications
Chromeno[3,4-b]xanthones as First-in-Class AChE and A beta Aggregation Dual-Inhibitors
10.3390/ijms22084145
Amyloid-beta and tau aggregation dual-inhibitors: A synthetic and structure-activity relationship focused review
10.1016/j.ejmech.2021.113209
2,2'-[(1E,1'E)-{[Hexa-2,4-diyne-1,6-diylbis(oxy)]bis(2,1-phenylene)}bis(ethene-2,1-diyl)]bis(4H-chromen-4-one)
10.3390/M1621
Recent Advances in Fluorescent Theranostics for Alzheimer's Disease: A Comprehensive Survey on Design, Synthesis, and Properties
10.1021/acsomega.3c10417
