Ana Teresa Rufino received her PhD degree in 2015 in Pharmacy at Coimbra University (Coimbra, Portugal) in the field of Pharmacology and pharmacotherapy of natural products and inflammation. Her research interests are the identification of natural products for therapeutic use as well as further validation and exploration of their potential use in different pathologies with a chronic inflammatory component. Currently, she is a researcher in an internationally recognized research Centre in the area of Green Chemistry, LAQV-REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
Representative Publications
Hyperglycemia and Hyperinsulinemia-Like Conditions Independently Induce Inflammatory Responses in Human Chondrocytes
10.3390/jfmk2020015
Assessment of cell line competence for studies of pharmacological GPR30 modulation.
Diabetes-induced osteoarthritis: role of hyperglycemia in joint destruction.
Differential effects of the essential oils of Lavandula luisieri and Eryngium duriaei subsp. juresianum in cell models of two chronic inflammatory diseases
10.3109/13880209.2014.970701
Evaluation of the anti-inflammatory, anti-catabolic and pro-anabolic effects of E-caryophyllene, myrcene and limonene in a cell model of osteoarthritis
10.1016/j.ejphar.2015.01.018
Anti-inflammatory and chondroprotective activity of (+)-α-pinene: Structural and enantiomeric selectivity
10.1021/np400828x
Resveratrol modulates cytokine-induced Jak/STAT activation more efficiently than 5-aminosalicylic acid: an in vitro approach.
10.1371/journal.pone.0109048
Expression and function of K(ATP) channels in normal and osteoarthritic human chondrocytes: Possible role in glucose sensing
10.1002/jcb.24532
Expression and function of the insulin receptor in normal and osteoarthritic human chondrocytes: Modulation of anabolic gene expression, glucose transport and GLUT-1 content by insulin
10.1016/j.joca.2011.02.004
Role of glucose as a modulator of anabolic and catabolic gene expression in normal and osteoarthritic human chondrocytes
10.1002/jcb.23196
Screening of five essential oils for identification of potential inhibitors of IL-1-induced Nf-κB activation and NO production in human chondrocytes: Characterization of the inhibitory activity of α-pinene
10.1055/s-0029-1186085
Expression and function of the nonclassical estrogen receptor, GPR30, in human cartilage and chondrocytes
10.1002/jcp.29691
