Research group
Chemistry and Bioactivity
Position
PhD student
BSc in Biochemistry, University of Aveiro (2014)
MSc in Biochemistry, specialization in Clinical Biochemistry, University of Aveiro (2016)
Juliana Calheiros is a PhD student of LAQV/REQUIMTE/FFUP/DRUG DISCOVERY & DEVELOPMENT RESEARCH UNIT (3D Unit), aiming to identify and validate new pharmacological modulators of BRCA1/2 function and DNA repair mechanisms, under the supervision of Prof. Lucília Saraiva.
Representative Publications
SLMP53-1 Inhibits Tumor Cell Growth through Regulation of Glucose Metabolism and Angiogenesis in a P53-Dependent Manner
10.3390/ijms21020596
BBIT20 inhibits homologous DNA repair with disruption of the BRCA1-BARD1 interaction in breast and ovarian cancer.
10.1111/bph.15506
Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance
10.3390/cancers13071648
Exploiting DNA Damage Repair in Precision Cancer Therapy: BRCA1 as a Prime Therapeutic Target
10.3390/cancers13143438
