Catarina Leal Seabra

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cseabra@ff.up.pt

Researcher IDAAD-3143-2020

Catarina L. Seabra (CLS) studied Biomedical Engineering with a major in Clinical Engineering at the University of Minho. In 2017, she got a PhD in Biomedical Sciences at ICBAS, University of Porto, in the development of a nanodelivery system to fight Helicobacter pylori gastric infection, and friendly to gut microbiota. She worked at i3S (2017-2018) and CQBF/Portuguese Catholic University (2018-2019), developing bioengineered strategies to fight pathogenic bacteria and to improve the welfare of gut microbiota.
Currently, she has been working at LAQV, developing nanoparticles to treat biofilms of multidrug resistant-bacterial infection.

Representative Publications

Uncovering Akkermansia muciniphila resilience or susceptibility to different temperatures, atmospheres and gastrointestinal conditions

10.1016/j.anaerobe.2019.102135

Nanostructured lipid carriers, methods and uses thereof (WO2018002853A1)

Nonantibiotic-Based Therapeutics Targeting Helicobacter pylori: From Nature to the Lab

10.5772/intechopen.81248

Influence of Saliva and Mucin on the Adhesion of Candida Oral Clinical Isolates

10.4236/jeas.2015.54018

The potential utility of chitosan micro/nanoparticles in the treatment of gastric infection

10.1586/14787210.2014.930663

Differential Adherence and Expression of Virulence Traits by Candida albicans and Candida parapsilosis in Mono- and Dual-Species Cultures in Artificial Saliva

10.1007/s11046-013-9661-0

Docosahexaenoic acid loaded lipid nanoparticles with bactericidal activity against Helicobacter pylon

10.1016/j.ijpharm.2017.01.014

A 17-mer Membrane-Active MSI-78 Derivative with Improved Selectivity toward Bacterial Cells

10.1021/acs.molpharmaceut.5b00113

Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78

10.1016/j.bbamem.2015.02.001

Lipid nanoparticles to counteract gastric infection without affecting gut microbiota

10.1016/j.ejpb.2018.02.030

Orally administrated chitosan microspheres bind Helicobacter pylori and decrease gastric infection in mice

10.1016/j.actbio.2020.06.035

Commensal obligate anaerobic bacteria and health: production, storage and delivery strategies

10.3389/fbioe.2020.00550

Nanoprobiotics: when technology meets gut health

10.1007/978-3-030-41464-1_17

Chitosan microspheres can fight Helicobacter pylori gastric infection in mice

10.3389/conf.fbioe.2016.01.02695

Drug Targeting of Inflammatory Bowel Diseases by Biomolecules

10.3390/nano11082035

Solids Turn into Liquids-Liquid Eutectic Systems of Pharmaceutics to Improve Drug Solubility

10.3390/ph15030279

Grafting MSI-78A onto chitosan microspheres enhances its antimicrobial activity

10.1016/j.actbio.2021.09.063

Metabolic profile of Candida albicans and Candida parapsilosis interactions within dual-species biofilms

10.1093/femsec/fiac031

(Chemical) Bonding is what makes life possible

Catarina Leal Seabra

Representative Publications