Research group
Chemistry and Bioactivity
Position
Researcher
Patrícia Bacalhau has a background in supramolecular chemistry and holds a Ph.D. in Biochemistry from the University of Évora. Since 2013, Patrícia engaged the study of the biochemical mechanisms involved in Alzheimer’s and Parkinson’s diseases. Her main results involved the discovery of a lead compound with therapeutic benefits for AD. She’s a teacher and collaborator of the Chemistry Center at University of Évora.
Representative Publications
Insights into (S)-Rivastigmine inhibition of ButyrylCholinesterase (BuChE): Molecular Docking and Saturation Transfer Difference NMR (STD-NMR)
10.1016/j.bioorg.2016.06.002
Design, Synthesis and Bioassays of 3-Substituted-3-Hydroxyoxindoles for Cholinesterase Inhibition
10.1002/slct.201600932
Biocatalysis in Drug Development of Neurodegenerative diseases: a mini review
New cholinesterase inhibitors for Alzheimer's disease: Structure Activity Studies (SARs) and molecular docking of isoquinolone and azepanone derivatives
10.1016/j.bioorg.2016.05.004
