Research group
Nanoplatforms for Life
Position
Researcher
Mariana Ferreira is a Post-Doctoral researcher at LAQV-REQUIMTE - Nanoplatforms for Life, under the supervision of Professor Paula Gameiro. Her study is focused on the development of metallocomplexes to bypass some bacterial resistance mechanisms. The work comprises the characterization of complexes of transition metals, the study of interaction of the compounds with membrane mimetic systems, the assessment of biological activity and safety of the compounds. In this context, during the last decade she improved her technical skills of biophysical and biochemical techniques, especially potentiometry (determination of constants of metal complexes), spectroscopy (UV-vis and fluorescence - steady-state, anisotropy, lifetime), SPR and microbiology. She holds scientific supervision of students, and participates in academic juries. She is responsible for the microbiological unit at REQUIMTE/Department of Chemistry and Biochemistry of Faculty of Sciences of University of Porto (DQB-FCUP) since 2021.
Representative Publications
Fluoroquinolone Metalloantibiotics: A Promising Approach against Methicillin-Resistant Staphylococcus aureus
10.3390/ijerph17093127
The Unusual Aggregation and Fusion Activity of the Antimicrobial Peptide W-BP100 in Anionic Vesicles
10.3390/membranes13020138
Fluoroquinolone Metalloantibiotics to Bypass Antimicrobial Resistance Mechanisms: Decreased Permeation through Porins
10.3390/membranes11010003
Caffeic acid phenolipids in the protection of cell membranes from oxidative injuries. Interaction with the membrane phospholipid bilayer
10.1016/j.bbamem.2021.183727
Modelling Hyperglycaemia in an Epithelial Membrane Model: Biophysical Characterisation
10.3390/biom12101534
