Research group
Chemistry and Bioactivity
Position
Researcher
Romeu A. Videira (RV, male) was graduated in Biochemistry, University of Coimbra, in 1993, and achieved his Ph.D. degree in 2003, in Biochemistry - Biochemical Toxicology, University of Coimbra. From 1998-2009 he assumed duties as teaching assistant in Polytechnic Institute of Viseu (IPV). From July 2009 to 2015, RV was Assistant Investigator at University of Trás-os-Montes e Alto (UTAD). From April 2016 to the present, Romeu Videira is a senior investigator at LAQV@REQUIMTE, developing his investigation within the “Natural Products – Chemistry and Bioactivity” research group at Faculty of Pharmacy of University of Porto. From 11/01/22, Romeu Videira is supported by a research contract under Scientific Employment Stimulus, reference CEECINST/00136/2021/CP2820/CT0001. He is author/co-author of 5 book chapters, 1 international Patent Application and 67 scientific peer-reviewed articles. Romeu A. Videira was awarded in “9º Concurso Nacional Poliempreende2012”- A national competition for entrepreneurship project ideas supported by a Portuguese Governmental Agency. Romeu Videira is interested to unveil the molecular mechanisms underlying the interconnectivity among mitochondrial activity, cell redox state and cell-to-cell communication processes. He uses biochemical, metabolomics and lipidomic approaches to investigate how the breakdown of this process is related with neurodegenerative diseases. Carbon nanomaterials and natural products-based nanotechnological approaches to fight against neurodegenerative disease is the focus of his investigation. Romeu A. Videira was PI of 3 National/international competitive projects and team member of other 6 projects. He is/was Supervisor/Co-supervisor of 10 M.Sc. students and 5 Ph.D. students (3 concluded and 2 ongoing).
Representative Publications
Cardiolipin profile changes are associated to the early synaptic mitochondrial dysfunction in Alzheimer's disease
10.3233/JAD-141002
Brain Effects of SC-Nanophytosomes on a Rotenone-Induced Rat Model of Parkinson's Disease-A Proof of Concept for a Mitochondria-Targeted Therapy
10.3390/ijms232012699
Mitochondrial Dysfunction in Skeletal Muscle of Rotenone-Induced Rat Model of Parkinson's Disease: SC-Nanophytosomes as Therapeutic Approach
10.3390/ijms242316787
Adding value to polyvinylpolypyrrolidone winery residue: A resource of polyphenols with neuroprotective effects and ability to modulate type 2 diabetes-relevant enzymes
10.1016/j.foodchem.2020.127168
A new insight on elderberry anthocyanins bioactivity: Modulation of mitochondrial redox chain functionality and cell redox state
10.1016/j.jff.2019.03.019
A nanophytosomes formulation based on elderberry anthocyanins and Codium lipids to mitigate mitochondrial dysfunctions
10.1016/j.biopha.2021.112157