LAQV REQUIMTE

(Chemical) Bonding is what makes life possible

José Domingos Santos

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Research group
Materials for Sustainability and Wellness

Position
Academic Staff

Researcher IDQ-9462-2018
Ciência ID3B1B-2F9B-319E
José Domingos Santos is Asociate Professor with Habilitation (Aggregation) at Faculty of Engineering, University of Porto. Has actively participated in 24 Research Projects financed by International institutions, coordinating 10 of them. Has been involved in the supervision of 8 Post-Docs, 23 PhDs and 24 MSc. With a h-index of 37, he has published 167 scientific papers in International scientific journals, edited 3 books and 16 book chapters. Co-inventor of 6 International Patents in Biomaterials which have resulted in trademarks bone grafts, as Bonelike® and Actifuse®. He is founding member of 3 start-up companies that operate in the Health Sciences, Medmat Innovation Lda, Biosckin - Molecular and Cell Therapies SA and Genetyca-ICM SA.

Representative Publications

Development of asymmetric resorbable membranes for guided bone and surrounding tissue regeneration
10.1002/jbm.a.36420
Processing, Characterization, and in Vivo Evaluation of Poly(l-lactic acid)-Fish Gelatin Electrospun Membranes for Biomedical Applications
10.1021/acsabm.8b00023
The Potential Clinical Application of Mesenchymal Stem Cells from the Dental Pulp (DPSCs) for Bone Regeneration
10.2174/9781681084770117060004
The benefit of bone marrow concentrate in addition to a glass-reinforced hydroxyapatite for bone regeneration: An in vivo ovine study
10.1002/jor.22800
Evaluation of PVA biodegradable electric conductive membranes for nerve regeneration in axonotmesis injuries: the rat sciatic nerve animal model
10.1002/jbm.a.35998
Clinical Application of Macroporous Ceramic to Promote Bone Healing in Veterinary Clinical Cases
10.5772/intechopen.70341
Scaffolds for Peripheral Nerve Regeneration, the Importance of In Vitro and In Vivo Studies for the Development of Cell-Based Therapies and Biomaterials: State of the Art
10.5772/intechopen.69540
Structure, Morphology and Bioactivity of Bioactive Glass Derived Xerogel and Aerogel
10.12816/0044600
Inflammatory response to dextrin-based hydrogel associated with human mesenchymal stem cells, urinary bladder matrix and Bonelike®granules in rat subcutaneous implants
10.1088/1748-6041/11/6/065004
Peripheral Nerve Regeneration: Current Status and New Strategies Using Polymeric Materials
10.1002/adhm.201600236
Therapeutic Strategies for Bone Regeneration: The Importance of Biomaterials Testing in Adequate Animal Models
10.1002/9781119242666.ch6
Preparation and characterization of electrical conductive PVA based materials for peripheral nerve tube-guides
10.1002/jbm.a.35730
Evaluation of biodegradable electric conductive tube-guides and mesenchymal stem cells
10.4252/wjsc.v7.i6.956
Neuro-muscular Regeneration Using Scaffolds with Mesenchymal Stem Cells (MSCs) Isolated from Human Umbilical Cord Wharton's Jelly: Functional and Morphological Analysis Using Rat Sciatic Nerve Neurotmesis Injury Model
10.1016/j.proeng.2015.07.016
Trends in Mesenchymal Stem Cells' Applications for Skeletal Muscle Repair and Regeneration
10.5772/60919
The role of hybrid chitosan membranes on scarring process following lumbar surgery: post-laminectomy experimental model
10.1179/1743132814y.0000000414
Morphology effect of bioglass-reinforced hydroxyapatite (Bonelike®) on osteoregeneration
10.1002/jbm.b.33195
Preparation andin vitrocytocompatibility of chitosan-siloxane hybrid hydrogels
10.1002/jbm.a.35171
A new sheep model with automatized analysis of biomaterial-induced bone tissue regeneration
10.1007/s10856-014-5216-2
Bone Marrow Stem Cells Added to a Hydroxyapatite Scaffold Result in Better Outcomes after Surgical Treatment of Intertrochanteric Hip Fractures
10.1155/2014/451781
Cell Therapy with Human MSCs Isolated from the Umbilical Cord Wharton Jelly Associated to a PVA Membrane in the Treatment of Chronic Skin Wounds
10.7150/ijms.9139
Challenges for Nerve Repair Using Chitosan-Siloxane Hybrid Porous Scaffolds
10.1155/2014/153808
Effects of Human Mesenchymal Stem Cells Isolated from Wharton’s Jelly of the Umbilical Cord and Conditioned Media on Skeletal Muscle Regeneration Using a Myectomy Model
10.1155/2014/376918
Guided bone regeneration using glass-reinforced hydroxyapatite and collagen membrane in the treatment of peri-implantitis
10.4028/www.scientific.net/SSP.207.109
Promoting Nerve Regeneration in a Neurotmesis Rat Model Using Poly(DL-lactide-ε-caprolactone) Membranes and Mesenchymal Stem Cells from the Wharton’s Jelly:In VitroandIn VivoAnalysis
10.1155/2014/302659
Treatment of a large cystic lesion in anterior maxilla using glass reinforced hydroxyapatite - A case report
10.4028/www.scientific.net/SSP.207.97
Biological evaluation of alginate-based hydrogels, with antimicrobial features by Ce(III) incorporation, as vehicles for a bone substitute
10.1007/s10856-013-4971-9
Biological evaluation of alginate-based hydrogels, with antimicrobial features by Ce(III) incorporation, as vehicles for a bone substitute
10.1007/s10856-013-4971-9
Nerve regeneration by using of chitosan-silicate hybrid porous membranes
10.4028/www.scientific.net/KEM.529-530.361
Development and characterization of novel alginate-based hydrogels as vehicles for bone substitutes
10.1016/j.carbpol.2013.02.067
Current trends on glass and ceramic materials
10.2174/97816080545271130101
Incorporation of glass-reinforced hydroxyapatite microparticles into poly(lactic acid) electrospun fibre mats for biomedical applications
10.1016/j.msec.2017.03.007
Long term performance evaluation of small-diameter vascular grafts based on polyvinyl alcohol hydrogel and dextran and MSCs-based therapies using the ovine pre-clinical animal model.
10.1016/j.ijpharm.2017.02.043
Multifunctional PLLA-ceramic fiber membranes applications for bone regeneration
10.1016/j.jcis.2017.05.032
Effect of sterilization methods on electrospun poly(lactic acid) (PLA) fiber alignment for biomedical applications
10.1021/acsami.5b10869
Novel cerium doped glass-reinforced hydroxyapatite with antibacterial and osteoconductive properties for bone tissue regeneration
10.1088/1748-6041/10/5/055008
In vitro and in vivo evaluation of blood coagulation activation of polyvinyl alcohol hydrogel plus dextran-based vascular grafts
10.1002/jbm.a.35275
The benefit of a human bone marrow stem cells concentrate in addition to an inorganic scaffold for bone regeneration: An in vitro study
10.1155/2015/240698
Samarium doped glass-reinforced hydroxyapatite with enhanced osteoblastic performance and antibacterial properties for bone tissue regeneration
10.1039/c4tb00484a
Biomaterials and Stem Cell Therapies for Injuries Associated to Skeletal Muscular Tissues
10.5772/53335
Calcium phosphate ceramics in periodontal regeneration
10.2174/9781608054527113010009
Development and characterization of lanthanides doped hydroxyapatite composites for bone tissue application
10.2174/9781608054527113010008