LAQV REQUIMTE

(Chemical) Bonding is what makes life possible

Ana Figueiras

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Research group
Nanoplatforms for Life

Position
Academic Staff

Researcher IDK-7332-2014
Ciência ID6812-91D2-837E
Ana Figueiras is Researcher and Assistant Professor in the Faculty of Pharmacy in the University of Coimbra. Her main objective is to combine know-how development during her Ph.D thesis and new strategies for successful drug delivery, especially in what concerns the use of block copolymers and micellar systems in cancer pathologies. She has published some pioneering works in micelleplexes as nanosystems for gene delivery (68 papers in international peer reviewed journals, 2 books and 15 book chapters), corresponding to a h-index of 29.

Representative Publications

Current progress on microRNAs-based therapeutics in neurodegenerative diseases
10.1002/wrna.1409
Smart micelleplexes as a new therapeutic approach for RNA delivery
10.1080/17425247.2016.1214567
Poloxamers, poloxamines and polymeric micelles: Definition, structure and therapeutic applications in cancer
10.1007/s10965-017-1426-x
miR-145-loaded micelleplexes as a novel therapeutic strategy to inhibit proliferation and migration of osteosarcoma cells
10.1016/j.ejps.2018.07.021
Epithelial-mesenchymal transition and microRNAs: Challenges and future perspectives in oral cancer
10.1002/hed.25381
RNAi-based therapeutics for lung cancer: biomarkers, microRNAs, and nanocarriers
10.1080/17425247.2018.1517744
The potential of micelleplexes as a therapeutic strategy for osteosarcoma disease
10.1007/s13205-020-2142-5
Nanomedicine in osteosarcoma therapy: Micelleplexes for delivery of nucleic acids and drugs toward osteosarcoma-targeted therapies
10.1016/j.ejpb.2019.10.013
Nanotheranostic Pluronic-Like Polymeric Micelles: Shedding Light into the Dark Shadows of Tumors
10.1021/acs.molpharmaceut.9b00945
Nanomedicine in osteosarcoma therapy: micelleplexes for co-delivery of nucleic acids and drugs for osteosarcoma-targeted therapies
Polymeric micelles for oral drug administration enabling locoregional and systemic treatments
10.1517/17425247.2015.960841
Supramolecular gels of poly-α-cyclodextrin and PEO-based copolymers for controlled drug release
10.1016/j.ejpb.2014.04.006
Characterization of polyplexes involving small RNA
10.1016/j.jcis.2012.07.088
Micelleplex-based nucleic acid therapeutics: From targeted stimuli-responsiveness to nanotoxicity and regulation
10.1016/j.ejps.2020.105461
Micelleplexes as nucleic acid delivery systems for cancer-targeted therapies
10.1016/j.jconrel.2020.04.041