Research group
Chemistry and Bioactivity
Position
Technician
José Miguel Pimenta Ferreira de Oliveira graduated in Biochemistry in 2000 (Faculty of Sciences, U.Porto). In 2010, completed his PhD degree in Life Sciences (Wageningen University). In 2011, joined as postdoctoral researcher the Stress Biology group led by Professor Conceição Santos (U.Aveiro), and in 2017 joined the Free Radicals and Antioxidants Unit led by Prof. Eduarda Fernandes (Faculty of Pharmacy, U.Porto).
The earlier postdoctoral activities focused on the antioxidant and cytotoxic effects of phytochemicals, e.g. cellular and molecular effects of flavonoids in different models. In addition, currently studies the cytotoxic and inhibitory actions of phytochemicals,e.g. flavonoids in osteosarcoma spheroids and in ex ovo cell models.
Representative Publications
Combination of etoposide and fisetin results in anti-cancer efficiency against osteosarcoma cell models
10.1007/s00204-017-2146-z
Biochemical and transcriptional analyses of cadmium-induced mitochondrial dysfunction and oxidative stress in human osteoblasts
10.1080/15287394.2018.1485122
Therapeutic potential of hesperidin and its aglycone hesperetin: Cell cycle regulation and apoptosis induction in cancer models
10.1016/j.phymed.2019.152887
β-Carotene and its physiological metabolites: Effects on oxidative status regulation and genotoxicity in in vitro models
10.1016/j.fct.2020.111392
