LAQV REQUIMTE

(Chemical) Bonding is what makes life possible

Sandra G Silva

Back

Research group
Molecular Synthesis

Position
Researcher

Researcher IDP-5443-2015
Ciência ID7312-63D5-220A
Sandra G. Silva (SGS) got her Chemistry degree in 2006 and her M.Sc. in Organic Chemistry in 2008, at Faculty of Science of University of Porto (FCUP). SGS obtained the PhD degree in Organic and Physical Chemistry (FCUP) in 2014. Her PhD work was devoted to the design, synthesis and physicochemical characterization of amino acid-based surfactants. From 2015 to 2016 SGS was Post-Doc researcher at 3B’s Research group (UM), working on the functionalization of biopolymers. Since 2016 SGS is a researcher at LAQV-REQUIMTE. In 2018, SGS was awarded a 6-year contract grant funded by FCT (Junior Reseacher) to work on a project that aims at the development of nanosystems (using amino acid-based surfactants) for the treatment of infectious diseases.

Representative Publications

Enhancing glioblastoma cell sensitivity to chemotherapeutics: A strategy involving survivin gene silencing mediated by gemini surfactant-based complexes
10.1016/j.ejpb.2016.04.014
Size, charge, and stability of fully serine-based catanionic vesicles: Towards versatile biocompatible nanocarriers
10.1002/chem.201406111
Effective cytocompatible nanovectors based on serine-derived gemini surfactants and monoolein for small interfering RNA delivery
10.1016/j.jcis.2020.09.077
Current Status of Amino Acid-Based Permeation Enhancers in Transdermal Drug Delivery
10.3390/membranes11050343
Serine-based surfactants as effective antimicrobial agents against multiresistant bacteria
10.1016/j.bbamem.2022.183969