The MS Facility at LAQV-U. Aveiro is integrated into the Portuguese Mass Spectrometry Network (RNEM). RNEM is a distributed National Research Infrastructure that integrates the Portuguese Roadmap of Research Infrastructures. Currently, we develop many research projects mainly focused on omics (Proteomics, Lipidomics, and Glycomics) applications to biochemistry and health sciences. The facility is also strongly committed in providing MS services to support external and in-house biochemistry, biology, chemistry, and bioengineering research groups. The MS facility of LAQV-UPORTO is part of the Structural Analysis Laboratory of the University of Porto Materials Center (CEMUP). The available spectrometers provide routine services to support in-house researchers, graduate, and postgraduate students as well as external users.