LAQV REQUIMTE

(Chemical) Bonding is what makes life possible

Sofia Antunes Costa Lima

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Research group
Nanoplatforms for Life

Position
Researcher

Researcher IDD-7026-2013
Ciência ID0013-8CA6-2D1C
Sofia Lima completed a PhD degree in Chemistry (UPorto), focused on biophysics for characterization of a membrane protein transporter. Subsequently was a PostDoc researcher at IBMC (currently I3S) for 5-years working on parasitology (in vitro and in vivo models of trypanosomatid infections), nanomedicine (development of drug delivery systems (DDS) for intracellular pathogens) and immunology (interactions of DDS with the immune system). Since 2013, Sofia Lima joined REQUIMTE as Assistant Researcher to apply the knowledge acquired in DDS to cancer and skin-inflammatory related diseases, achieving recognition as co-author of > 50 international peer-reviewed publications, student’s supervision and attaining funded projects on skin research.

Representative Publications

Cellular interactions of a lipid-based nanocarrier model with human keratinocytes: Unravelling transport mechanisms
10.1016/j.actbio.2017.01.057
Multifunctional nanospheres for co-delivery of methotrexate and mild hyperthermia to colon cancer cells
10.1016/j.msec.2017.03.049
Optimization of nanostructured lipid carriers loaded with methotrexate: A tool for inflammatory and cancer therapy
10.1016/j.ijpharm.2015.07.013
Temperature-responsive polymeric nanospheres containing methotrexate and gold nanoparticles: A multi-drug system for theranostic in rheumatoid arthritis
10.1016/j.colsurfb.2015.04.048
A new topical formulation for psoriasis: Development of methotrexate-loaded nanostructured lipid carriers
10.1016/j.ijpharm.2014.10.067