Research group
Nanoplatforms for Life
Position
Researcher
Sofia Lima (SL) graduated in Microbiology, completed a MSc in Biotechnology by De Montfort University (UK) and hold a PhD in Chemistry (UPorto). Currently, SL is an assistant researcher, under Institutional Call to Scientific Employment Stimulus (Inst-CEEC, 2022) at the School of Medicine and Biomedical Sciences (ICBAS, UPorto), and an integrated member of the LAQV-REQUIMTE. SL was awarded with an assistant researcher position in the Individual CEEC (2019) and with a principal researcher position in Individual CEEC (2022).
SL main research activity is focused on development of functionalized nanoplatforms and their application in the pharmaceutical and nutrition fields. She is also specialized in in vitro disease modelling to validate functionalized nanomedicines and to perform in vitro/in vivo correlations. SL has supervised/co-supervised 1 junior researcher, 7 PhD students, 12 mobility MSc/PhD students,16 MSc student and 28 research trainees. As of June 2024, SL is the author of 88 articles in journals (75% Q1), 40% as corresponding author cited over 2700 times corresponding to an h-index of 30 (scopus). SL is also the co-author of 1 book, 3 invited book chapters and a national provisional patent. SL enjoys international recognition being: a reviewer for international journals, an evaluator in national and international scientific projects, and was invited for oral communications of work. Furthermore, SL participated in four COST Actions as science communication manager, management committee member and working group member and currently integrates two networking projects [CA22160 and CA21108].
SL is a member of the One Health Office at ICBAS and carries out educational activities. In addition to being a partner in several research projects, SL has been PI of competitively funded projects (FCT and Gulbenkian) and bilateral collaborative projects.
Representative Publications
Multifunctional nanospheres for co-delivery of methotrexate and mild hyperthermia to colon cancer cells
10.1016/j.msec.2017.03.049
Cellular interactions of a lipid-based nanocarrier model with human keratinocytes: Unravelling transport mechanisms
10.1016/j.actbio.2017.01.057
Modulation of Macrophages M1/M2 Polarization Using Carbohydrate-Functionalized Polymeric Nanoparticles
10.3390/polym13010088
Design and Characterization of Sodium Alginate and Poly(vinyl) Alcohol Hydrogels for Enhanced Skin Delivery of Quercetin
10.3390/pharmaceutics12121149
Targeting the Mannose Receptor with Functionalized Fucoidan/Chitosan Nanoparticles Triggers the Classical Activation of Macrophages
10.3390/ijms24129908