Research group
Nanoplatforms for Life
Position
Academic Staff
Paula Gameiro research activities are focused on the biophysical and biological study of drugs interaction with biological membranes. The main research goal being the development of new materials and strategies to fight antibiotic-resistant infections.
Paula research goals include (i) use and development of spectroscopic and microscopic techniques to study biological membrane changes related with the mechanism of action/resistance of antibiotics (fluoroquinolone, fluoroquinolone metalloantibiotics and antimicrobial peptides/metallopeptides), (ii) biological and biophysical study of antimicrobial activity, bacteria biofilms, and bacterial membrane fluidity.
Representative Publications
The binding of free and copper-complexed fluoroquinolones to OmpF porins: an experimental and molecular docking study
10.1039/c6ra26466b
Evaluation of membrane fluidity of multidrug-resistant isolates of Escherichia coli and Staphylococcus aureus in presence and absence of antibiotics
10.1016/j.jphotobiol.2018.03.002
Antibacterial activity of naphthyl derived bis-(3-hydroxy-4-pyridinonate) copper(II) complexes against multidrug-resistant bacteria
10.1016/j.jinorgbio.2019.110704
Intragenic Antimicrobial Peptide Hs02 Hampers the Proliferation of Single- and Dual-Species Biofilms of P. aeruginosa and S. aureus: A Promising Agent for Mitigation of Biofilm-Associated Infections
10.3390/ijms20143604
