Research group
Chemistry and Bioactivity
Position
Researcher
Marisa Freitas (MF) completed her PhD degree in Pharmaceutical Sciences in 2010, in Faculty of Pharmacy of University of Porto. In 2012, MF was awarded with a post-Doc FCT fellowship and in 2016 she was hired as Researcher from the project-NORTE-01-0145-FEDER-000024. In April of 2019, MF was hired as Researcher in the project- POCI-01-0145-FEDER-029248. In 2020 MF won a grant in the Call for Individual Scientific Employment Stimulus from FCT (2020.04126.CEECIND). In 2021, MF was hired as an Assistant Researcher, becoming part of the permanent staff at REQUIMTE. Her high scientific competence is evidenced by the +110 papers [h-index of 40 (Scopus) and 23000+ citations] and 36 abstracts published in international indexed journals, 9 book chapters, 55 oral communications and 140+ poster communications in national and international conferences. MF was Principal Investigator of one funded project and participated as executive researcher in 20 projects funded by national and international agencies . MF is at themoment responsible for the supervision of several students: 3 PhD and 1 Master and completed the supervision of 1 PhD, 7 Msc, 17 academic stages and 4 students on a mobility program. MF enjoys international recognition evidenced by being: researcher of three COST actions [CA15129, CA16119, CA20121], External Advisor in the Global Burden of Disease Studies Study, peer-reviewer for +20 journals (Publons- Web of Science ResearcherIDAAY-7427-2020), international scientific projects evaluator. Furthermore, MF carries out educational activities through invited lectures at graduation and post-graduation courses.
Representative Publications
Polyacrylic acid-coated and non-coated iron oxide nanoparticles induce cytokine activation in human blood cells through TAK1, p38 MAPK and JNK pro-inflammatory pathways
10.1007/s00204-014-1325-4
Iron Oxide Nanoparticles: An Insight into their Biomedical Applications
Pyrazoles have a multifaceted anti-inflammatory effect targeting prostaglandin E2, cyclooxygenases and leukocytes’ oxidative burst
10.1016/j.biocel.2024.106599
Inhibition of protein tyrosine phosphatase 1B by flavonoids: A structure activity relationship study
10.1016/j.fct.2017.11.039
Inhibitory activity of flavonoids against human sucrase-isomaltase (alpha-glucosidase) activity in a Caco-2/TC7 cellular model
10.1039/d1fo02995a
An In Silico and an In Vitro Inhibition Analysis of Glycogen Phosphorylase by Flavonoids, Styrylchromones, and Pyrazoles
10.3390/nu14020306
Silver nanoparticles exert toxic effects in human monocytes and macrophages associated with the disruption of Delta psi m and release of pro-inflammatory cytokines
10.1007/s00204-022-03415-x
Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice
10.1007/s00204-023-03558-5
Melanoxetin: A Hydroxylated Flavonoid Attenuates Oxidative Stress and Modulates Insulin Resistance and Glycation Pathways in an Animal Model of Type 2 Diabetes Mellitus
10.3390/pharmaceutics16020261
