Natural Products – Chemistry and Bioactivity
Degree in Pharmaceutical Sciences (1997), PhD in Pharmacology (2004), Faculty of Pharmacy, University of Porto (FFUP). Assistant Professor, Laboratory of Pharmacology, FFUP.
Research: pathophysiology of renin-angiotensin system in cardiovascular and inflammatory diseases. Hypertension, heart failure, diabetes, obesity, renal disease. Inflammatory bowel disease. Clinical and experimental models. Certificated to work with laboratory animals.
Supervisor of 8 PhD students, 10 Master students, and of several undergraduates. PI of 3 research projects and co-PI of 9. Several awards within scientific meetings.
Published 1 book chapter, 5 review papers, 1 letter to the Editor, and 19 original papers in international journals with peer-review.
Unraveling the Role of ACE2, the Binding Receptor for SARS-CoV-2, in Inflammatory Bowel Disease
Association of myeloperoxidase levels with cardiometabolic factors and renal function in prepubertal children
Attenuated Aortic Vasodilation and Sympathetic Prejunctional Facilitation in Epinephrine-Deficient Mice: Selective Impairment of beta(2)-Adrenoceptor Responses
Diabetes-induced increase of renal medullary hydrogen peroxide and urinary angiotensinogen is similar in normotensive and hypertensive rats
Angiotensin II contributes to glomerular hyperfiltration in diabetic rats independently of adenosine type I receptors
Functional crosstalk of prejunctional receptors on the modulation of noradrenaline release in mesenteric vessels: A differential study of artery and vein
Does Chronic Pain Alter the Normal Interaction Between Cardiovascular and Pain Regulatory Systems? Pain Modulation in the Hypertensive-Monoarthritic Rat
Renal effects of adenosine on diabetic Wistar and SHR rats
Effect of 2-chloroadenosine on sodium and potassium excretion in diabetic Wistar and SHR rats
Endogenous and exogenous adenosine and structural alterations in diabetic nephropathy: a possible role of the renin-angiotensin system?