Research group
Chemistry and Bioactivity
Position
Academic Staff
Degree in Pharmaceutical Sciences (1997), PhD in Pharmacology (2004), Faculty of Pharmacy, University of Porto (FFUP). Assistant Professor, Laboratory of Pharmacology, FFUP.
Research: pathophysiology of renin-angiotensin system in cardiovascular and inflammatory diseases. Hypertension, heart failure, diabetes, obesity, renal disease. Inflammatory bowel disease. Clinical and experimental models. Certificated to work with laboratory animals.
Supervisor of 8 PhD students, 10 Master students, and of several undergraduates. PI of 3 research projects and co-PI of 9. Several awards within scientific meetings.
Published 1 book chapter, 5 review papers, 1 letter to the Editor, and 19 original papers in international journals with peer-review.
Representative Publications
Association of myeloperoxidase levels with cardiometabolic factors and renal function in prepubertal children
10.1111/eci.12564
Attenuated Aortic Vasodilation and Sympathetic Prejunctional Facilitation in Epinephrine-Deficient Mice: Selective Impairment of beta(2)-Adrenoceptor Responses
10.1124/jpet.114.217281
Diabetes-induced increase of renal medullary hydrogen peroxide and urinary angiotensinogen is similar in normotensive and hypertensive rats
10.1016/j.lfs.2014.05.011
Angiotensin II contributes to glomerular hyperfiltration in diabetic rats independently of adenosine type I receptors
10.1152/ajprenal.00285.2012
Functional crosstalk of prejunctional receptors on the modulation of noradrenaline release in mesenteric vessels: A differential study of artery and vein
10.1016/j.ejphar.2010.10.075
Does Chronic Pain Alter the Normal Interaction Between Cardiovascular and Pain Regulatory Systems? Pain Modulation in the Hypertensive-Monoarthritic Rat
10.1016/j.jpain.2010.06.009
Renal effects of adenosine on diabetic Wistar and SHR rats
Endogenous and exogenous adenosine and structural alterations in diabetic nephropathy: a possible role of the renin-angiotensin system?
Effect of 2-chloroadenosine on sodium and potassium excretion in diabetic Wistar and SHR rats
Unraveling the Role of ACE2, the Binding Receptor for SARS-CoV-2, in Inflammatory Bowel Disease
10.1093/ibd/izaa249