Research group
Food Quality and Technology
Position
Junior Researcher
Ana Margarida Araújo is currently a Junior Researcher at the associated laboratory LAQV/REQUIMTE at the Faculty of Pharmacy of the University of Porto. She has a PhD in Pharmaceutical Sciences from the University of Porto (2021). Her main domain of expertise is in the field of metabolomics, where she applies cutting-edge analytical techniques [such as gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS)] to assess the metabolic profile of a wide variety of samples (cells, tissues, biofluids, as well as food and environmental matrices). She also has extensive experience in bioinformatics/statistical analysis of complex datasets using open source programming languages. Her primary area of interest lies on the use of metabolomics as a holistic and highly sensitive tool for comprehending complex systems and explore them to study specific physiological issues, pathological mechanisms and assess environmental impacts.
Representative Publications
Synthetic cannabinoids JWH-122 and THJ-2201 disrupt endocannabinoid-regulated mitochondrial function and activate apoptotic pathways as a primary mechanism of in vitro nephrotoxicity at in vivo relevant concentrations.
10.1093/toxsci/kfz050
GC-MS Metabolomics Reveals Distinct Profiles of Low- and High-Grade Bladder Cancer Cultured Cells
10.3390/metabo9010018
3,4-Methylenedioxymethamphetamine Hepatotoxicity under the Heat Stress Condition: Novel Insights from in Vitro Metabolomic Studies
10.1021/acs.jproteome.9b00741
In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV)
10.1007/s00204-020-02949-2
