Research group
Molecular Synthesis
Position
Academic Staff
Maria Rangel is Full Professor at ICBAS-UP. Teaches courses on Chemical Biology, Biophysics and Spectroscopy. MR is Co-Director of MIB-UP; Member of CCCT REQUIMTE and Scientist in charge of NMR and EPR Laboratories of UP.
MR is a Bioinorganic Chemist whose research interest is the role of metal ions in living organisms. MR works on the design of Fe chelators to fight Infection, Fe Overload and Fe Sensing. More recently she works in Plant Fe Nutrition.
Insulin-like V and Zn compounds and the study of B12 model compounds are other topics that are under investigation.
MR has been Principal Investigator of several multidisciplinary projects coordinating research teams on the interfaces of chemistry and biology.
Representative Publications
Effect of tris(3-hydroxy-4-pyridinonate) iron(III) complexes on iron uptake and storage in soybean (Glycine max L.)
10.1016/j.plaphy.2016.04.050
Relevant Interactions of Antimicrobial Iron Chelators and Membrane Models Revealed by Nuclear Magnetic Resonance and Molecular Dynamics Simulations
10.1021/jp509491p
EPR and XANES studies of anaerobic photolysis of iso-propilpyridinecobaloxime: Elucidation of the reactivity of the Co(II) primary product
10.1016/j.jorganchem.2014.01.033
Distinctive EPR signals provide an understanding of the affinity of bis-(3-hydroxy-4-pyridinonato) copper(II) complexes for hydrophobic environments
10.1039/c4dt00642a
Tuning the Anti(myco)bacterial Activity of 3-Hydroxy-4-pyridinone Chelators through Fluorophores
10.3390/ph11040110
A 1000-year-old mystery solved: Unlocking the molecular structure for the medieval blue from Chrozophora tinctoria, also known as folium
10.1126/sciadv.aaz7772
Synthesis, characterization, and cellular investigations of porphyrin-and chlorin-indomethacin conjugates for photodynamic therapy of cancer
10.1039/d1ob01015h
Non-transferrin-bound iron determination in blood serum using microsequential injection solid phase spectrometry- proof of concept
10.1016/j.talanta.2023.124345
Ohmic heating-assisted synthesis and characterization of Zn(ii), Cu(ii) and Pd(ii) complexes of heterocyclic-fused chlorins
10.1039/d1dt04032d
Foliar application of 3-hydroxy-4-pyridinone Fe-chelate [Fe(mpp)(3)] induces responses at the root level amending iron deficiency chlorosis in soybean
10.1111/ppl.13367
A combined physiological and biophysical approach to understand the ligand‐dependent efficiency of 3‐hydroxy‐4‐pyridinone Fe‐chelates
10.1002/pld3.256
NMR and EPR study of the interaction of tris(3-hydroxy-4-pyridinonato) Ga (III) complexes with liposomes that mimic plant membranes
10.1016/j.bpc.2023.107021
