LAQV REQUIMTE

Aluna do PDQS - Isabela Santos, conquista Bolsa Fulbright!

A FULBRIGHTER 2024 voa para a Harvard Medical School para desenvolver parte do seu trabalho experimental nos EUA

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Isabela Santos is a PhD student in Sustainable Chemistry at LAQV-REQUIMTE, Faculty of Pharmacy, University of Porto. Under the supervision of LAQV researchers Miguel Oliveira at University of Porto and Hélio Albuquerque at the University of Aveiro, Isabela's research project focuses on uncovering the therapeutic potential of natural compounds, specifically flavonoids, in targeting TGF-β in metastatic osteosarcoma.
With the support of a Fulbright grant, Isabela will embark on clinical research to develop new pharmacokinetic study models for osteosarcoma. She will join Professor Su Ryon Shin’s Lab in the Division of Engineering in Medicine at Brigham and Women's Hospital, Harvard Medical School (Boston). There, Isabela aims to pioneer a dynamic 3D osteosarcoma bone-on-a-chip platform. This innovative platform will enable her to monitor and analyze the interactions between osteosarcoma cells and bone tissues when exposed to flavonoid derivatives, providing valuable insights into potential treatment strategies. This endeavor aligns with New Approach Methodologies strategies within the context of Personalized Medicine, aiming to revolutionize the understanding and treatment of osteosarcoma.