History and proteomics in one image

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The (Bio)Chemistry & Omics research group has been dedicated to raise the name of Portugal overseas. After creating the Portuguese flag using chemistry and nanotechnology (Público) and the “Galo de Barcelos” by colouring different protein interactions (FCT-news), BCO has recently created the first circumnavigation to our planet by representing protein interactions and biochemical pathways.

This creative work will be the cover of the Journal of Proteomics, one of the most well-recognized international journals in the fields of biochemistry and proteomics. It was developed by Hugo Santos, José Capelo, and Carlos Lodeiro, all from the NOVA School of Science and Technology (FCT NOVA). Through this work, BCO aims to celebrate a unique event that took place 500 years ago. A Spanish and Portuguese expedition, composed by five ships, left Spain in September 1519, reaching Rio de Janeiro, and then heading south searching for a path to the “Spice Islands” that eventually were found in November 1520. They were the first Europeans sailing the Pacific, which was named by them. At the end of the expedition, only one ship and 18 sailors (of the initial 236) survived.

The figure is depicted as a series of nodes and edges, like the ones proteomics uses to describe proteins and their interactions. “In the same way that explorers travelled thousands of kilometres on this trip, we, biochemists, travel thousands of proteins and their interactions in order to unveil how tumours appear and evolve, how they can be treated, and anticipate whether a patient will respond better or worse to a particular treatment.”, says Hugo Santos. The global view of proteins is also a step forward in identifying new therapeutic targets.

This way, BCO is celebrating both an important mark in our history and the advances in Proteomics, combining history and proteomics in one image.

LAQV in the news: = Público =